Susceptibility and cellular responses of COPD airway epithelium to cigarette smoke in stem cell-derived ALI models
Jialei Jiang, Yushan Tian, Yinuo Zhao, Chen Tan, Xiao Li, Hongjuan Wang, Longjiang Fan, Hongyu Chen
This study compares the effects of high-tar and low-tar cigarette smoke on COPD airway epithelium using stem cell-derived ALI models, finding stronger responses to high-tar smoke across multiple molecular dimensions.
bioRxiv · Oct 29, 2026 · PreprintCell Biology