Yinuo Zhao

Susceptibility and cellular responses of COPD airway epithelium to cigarette smoke in stem cell-derived ALI models

This study compares the effects of high-tar and low-tar cigarette smoke on COPD airway epithelium using stem cell-derived ALI models, finding stronger responses to high-tar smoke across multiple molecular dimensions.

Intrinsic molecular susceptibility underlies selective neuronal vulnerability in the Alzheimer's disease entorhinal cortex

The paper identifies intrinsic molecular features of calbindin-expressing neurons in the entorhinal cortex that contribute to their vulnerability in Alzheimer's disease and suggests potential therapeutic targets.

OneGenome-Rice (OGR): A genomic foundation model for rice

OneGenome-Rice (OGR) is a genomic foundation model for rice pre-trained on 422 genomes, outperforming existing models in 11 tasks and enabling downstream applications like trait analysis and gene expression prediction.