Author

Jiangshan Bai

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:deep learning· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Organism:mouse· 1

Frequent Co-Authors

Aristotelis TsirigosiD· 2 shared Bo XiaiD· 2 shared Jimin TaniD· 2 shared Xinyu LingiD· 2 shared Anders S. HanseniD· 1 shared B BernsteiniD· 1 shared Bailey Tischer· 1 shared David FenyöiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Aristotelis TsirigosORCID

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2 papers

Recent·Most cited

High-throughput in silico screen uncovers key regulators of 3D genome architecture

Jiangshan Bai, Qingji Lyu, Jimin Tan, Robbyn Issner, Bailey Tischer, Hanqing Liu, Viraat Y. Goel, Xinyu Ling, B Bernstein, Aristotelis Tsirigos, Anders S. Hansen, Bo Xia

The paper identifies ZNF654 and JMJD6 as novel factors defining TAD boundaries through in silico screens and experimental validation.

bioRxiv · Dec 11, 2025 · PreprintGenomics

Decoding the gene regulatory landscape through multimodal learning of protein-DNA interactions

Jimin Tan, Xi Fu, Xinyu Ling, Shentong Mo, Jiangshan Bai, Raúl Rabadán, David Fenyö, Jef D. Boeke, Aristotelis Tsirigos, Bo Xia

Chromnitron predicts protein-DNA binding landscapes across cell types and proteins using multimodal learning, revealing new regulators of T cell exhaustion and dynamic shifts during neurogenesis.

bioRxiv · Aug 17, 2025 · PreprintSystems Biology

Jiangshan Bai · henhao