Author
Jimin Tan
Broad InstituteORCID 0000-0001-5912-3062Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2023-2025 · peak 6/yrCo-Author Collaboration Network
10 top collaborators · 33 mutual co-author links7 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Non-segmented unsupervised learning of multispectral whole slide images for robust analysis of tissue repair and regeneration
Kody Paul Mansfield, Tamara Mestvirishvili, Bibi S. Subhan…·Piul S. Rabbani
This paper introduces a segmentation-free method for analyzing multispectral whole slide images to study tissue repair and regeneration, revealing tissue compartments and dynamics without prior labels.
- Systems BiologybioRxivPreprint
Decoding the gene regulatory landscape through multimodal learning of protein-DNA interactions
Jimin Tan, Xi Fu, Xinyu Ling…·Bo Xia
Chromnitron predicts protein-DNA binding landscapes across cell types and proteins using multimodal learning, revealing new regulators of T cell exhaustion and dynamic shifts during neurogenesis.
2 citations - Cancer BiologybioRxivPreprint
A multi-scale segmentation-free self-supervised AI model to characterize the heterogeneity of the brain tumor microenvironment
Sam Sterling, Jimin Tan, Hortense Le…·Aristotelis Tsirigos
This paper introduces a segmentation-free self-supervised AI model to analyze brain tumor microenvironments, identifying a novel tumor-associated B cell subset linked to improved survival.
- Cancer BiologyNature Biomedical EngineeringPeer-reviewed
Characterization of tumor heterogeneity through segmentation-free representation learning
Jimin Tan, Hortense Le, Jiehui Deng…·David Fenyö
The paper introduces a segmentation-free vision transformer, CANVAS, to discover and characterize tumor microenvironment signatures from high-dimensional multiplexed images, identifying a monocytic signature linked to poor prognosis.
10 citations - BioinformaticsNaturePeer-reviewed
GET: a foundation model of transcription across human cell types
Xi Fu, Shentong Mo, Alejandro Buendia…·Raúl Rabadán
GET is a foundation model that accurately predicts gene expression and regulatory interactions across 213 human cell types using chromatin accessibility and sequence data.
- GenomicsNature BiotechnologyPeer-reviewed
Cell type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening
Jimin Tan, Nina Shenker-Tauris, Javier Rodriguez-Hernaez…·Aristotelis Tsirigos
This study introduces C.Origami, a deep learning model that predicts cell type-specific 3D chromatin organization, enabling in silico genetic screening to identify genomic regions affecting chromatin structure.