Cell BiologyJCI InsightPeer-reviewed
PI3Kγ promotes neutrophil extracellular trap formation by noncanonical pyroptosis in abdominal aortic aneurysm
Yacheng Xiong, Shuai Liu, Yu Liu…·Wei Wang
This study identifies PI3Kγ as a regulator of neutrophil extracellular trap formation in abdominal aortic aneurysm via noncanonical pyroptosis, showing its inhibition reduces inflammation and ameliorates AAA.
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