Author

Jianling Zhong

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Organism:yeast· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alexander J. HarteminkiD· 3 shared Alexias SafiiD· 1 shared Alok K. TewariiD· 1 shared David M. MacAlpineiD· 1 shared Gregory E. CrawfordiD· 1 shared Kaixuan LuoiD· 1 shared Li MaiD· 1 shared Linda K. Hong· 1 shared

Activity by Year

2015-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBioinformatics

Alexander J. HarteminkORCID

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3 papers

Recent·Most cited

Quantitative occupancy of myriad transcription factors from one DNase experiment enables efficient comparisons across conditions

Kaixuan Luo, Jianling Zhong, Alexias Safi, Linda K. Hong, Alok K. Tewari, Lingyun Song, Timothy E. Reddy, Li Ma, Gregory E. Crawford, Alexander J. Hartemink

The paper introduces TOP, a Bayesian framework that quantifies TF occupancy across many conditions using a single DNase-seq experiment, showing changes in 1500 TF motifs across cell types, hormone exposure, and genetic backgrounds.

Genome Research · Jun 1, 2022Peer-reviewedBioinformatics

RoboCOP: Jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data

Sneha Mitra, Jianling Zhong, Trung Q. Tran, David M. MacAlpine, Alexander J. Hartemink

RoboCOP computes chromatin occupancy profiles for multiple factors from epigenomic data, showing improved accuracy over existing methods for yeast nucleosomes and 150 TFs.

Nucleic Acids Research · Jul 8, 2021Peer-reviewedBioinformatics

Chromatin interactions correlate with local transcriptional activity in Saccharomyces cerevisiae

Zackary Scholl, Jianling Zhong, Alexander J. Hartemink

The paper examines chromatin interactions in yeast and finds that transcriptional activity correlates with chromosomal interactions.

bioRxiv · Jul 6, 2015 · PreprintBioinformatics