Mammalian TMC Family Proteins are Mechanically Gated Ion Channels
Songdi Fu, Jianying Dong, Xing Luo, Ting Xie, Wei Li, Yufei Luo, Zhiqiang Yan
The paper identifies TMC3-8 as mechanosensitive ion channels by showing their plasma membrane localization and stretch-activated currents in cultured cells.
bioRxiv · Aug 20, 2026 · PreprintNeuroscience