Unlocking Ultrasensitive Phosphoproteomics of Nanoscale Samples: A Rapid IMAC Enrichment Platform Using Ti-PAN Tip
Chunhua Wu, Yao Lin, Xingyao Wang, Jiawei Gong, Bing Liu, Y H Lü, Feitai Tang, Mei Yang, Ge Lin, Jue Zhang, Shen Zhang
This paper develops a rapid phosphopeptide enrichment method (Ti-PAN) for nanoscale samples, achieving high sensitivity and recovery, and identifies key kinases in oocyte maturation.
bioRxiv · Jan 8, 2026 · PreprintBiochemistry