A Neutrophil Defensin-VDAC1 Axis Drives Steatotic Liver Disease
Jue Zhang, Gan Luo, Gang Wang, Jie Rao, Xiao Li, Wuyuan Lu
This study identifies HNP-VDAC1 axis as a driver of MASLD by showing HNPs induce mitochondrial dysfunction and lipid accumulation in hepatocytes.
bioRxiv · Sep 28, 2026 · PreprintImmunology