Holotomography reveals biophysical remodeling of mouse oocytes during post-ovulatory aging
M U Kim, Chungha Lee, Jieun Do, Taeseop Shin, Daria Iliev, Kyoung Hee Choi, So Yeon Shin, 고지은, Teodora Popa, Cristina Fontes Lindemann Hickman, Ji Hyang Kim, YongKeun Park
This paper uses holotomography to analyze 3D biophysical changes in mouse oocytes during post-ovulatory aging, showing that non-morphological features better distinguish aged from fresh oocytes.
bioRxiv · Jun 19, 2026 · PreprintDevelopmental Biology