Secreted phospholipase A2α generates a pathogen-derived lysophospholipid to signal local immunity
Hyoung Yool Lee, 凌腾芳, Jihye Jung, Krishna Kumar, S C Kim, Sunyo Jung, Inhwan Hwang, Kyoungwhan Back, Stephen I. Ryu
The paper identifies lysophosphatidylethanolamine (LPE18:1) as an immune signal generated by host PLA2 enzyme from pathogen lipids, linking NLR activation to localized defense responses.
bioRxiv · May 18, 2026 · PreprintPlant Biology