Cholecystokinin 1 Receptor (Cck1R) Normalizes mTORC1 signaling and is Protective to Purkinje cells in SCA Mice
Emily A.L. Wozniak, Zhao Chen, Sharan Paul, Praseuth Yang, Karla Patricia Figueroa, Jill Friedrich, Tyler Tschumperlin, Michael Berken, Melissa A. C. Ingram, Christine M. Henzler, Stefan M. Pulst, Harry T. Orr
The paper shows that activating the Cck1R pathway reduces mTORC1 signaling and protects Purkinje neurons in SCA mouse models.
bioRxiv · Feb 16, 2021 · PreprintNeuroscience