Author

Christine M. Henzler

University of MinnesotaORCID 0000-0003-4566-2211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Harry T. OrriD· 2 shared Aaron KhaimrajiD· 1 shared Alberto OriolesiD· 1 shared Alexander K. JohnsoniD· 1 shared Alka KhaitaniD· 1 shared Alyssa SolesiD· 1 shared Angela Panoskaltsis‐MortariiD· 1 shared Beth Kristine ThieleniD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Harry T. OrrORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyJournal of the Pediatric Infectious Diseases SocietyPeer-reviewedOct 1, 2024

Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

Jenna K. Dick, Jules A. Sangala, Venkatramana Divana Krishna…·Geoffrey T. Hart

This study identifies dysregulated antibody-mediated cellular responses in MIS-C, linking NK cell dysfunction to immune pathology and suggesting potential therapeutic interventions.

3 citations

humanflow cytometry

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 16, 2021

Disrupting ATXN1 Nuclear Localization in a Knock-in SCA1 Mouse Model Improves a Spectrum of SCA1-Like Phenotypes and their Brain Region Associated Transcriptomic Profiles

Hillary P. Handler, Lisa A. Duvick, Jason S. Mitchell…·Harry T. Orr

This study shows disrupting ATXN1 nuclear localization in a SCA1 mouse model reduces disease-like phenotypes and alters region-specific transcriptomic profiles.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 16, 2021

Cholecystokinin 1 Receptor (Cck1R) Normalizes mTORC1 signaling and is Protective to Purkinje cells in SCA Mice

Emily A.L. Wozniak, Zhao Chen, Sharan Paul…·Harry T. Orr

The paper shows that activating the Cck1R pathway reduces mTORC1 signaling and protects Purkinje neurons in SCA mouse models.

DOI 10.1101/2021.02.16.431490

mouseexperimental assay

𝕏 PostBluesky