Systematic comparison and rational design of theophylline riboswitches for efficient gene repression
Xun Wang, Can Fang, Yifei Wang, Xinyu Shi, Fan Dong Yu, Jin Xiong, Shan‐Ho Chou, Jin He
The paper evaluates 25 theophylline riboswitches for gene repression in bacteria, finds limited effectiveness, and designs a more potent dual riboswitch system for efficient gene regulation.
bioRxiv · Jul 17, 2022 · PreprintSynthetic Biology