Comparative multi-omics analyses of cardiac mitochondrial stress in three mouse models of frataxin deficiency
Nicole M. Sayles, Jill S. Napierala, Josef Anrather, Nadège Diedhiou, Jixue Li, Марек Напиерала, Hélène M. Puccio, Giovanni Manfredi
The paper compares multi-omics data from three mouse models of partial frataxin deficiency to assess mitochondrial stress in the heart, finding mild transcriptional changes despite severe FXN reduction.
Disease Models & Mechanisms · Sep 11, 2023Peer-reviewedMolecular Biology