Cells transit through a quiescent-like state to convert to neurons at high rates
Adam M. Beitz, JMY Teves, Conrad G. Oakes, Christopher P. Johnstone, Nathan Wang, Joshua M. Brickman, Kate E. Galloway
The paper identifies a quiescent-like state with reduced nuclear size and transcriptional activity that enables efficient TF-mediated conversion of fibroblasts to neurons.
bioRxiv · Nov 22, 2024 · PreprintSystems Biology