Author

Joan Onwunma

University of Toledo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Banumathi SankaraniD· 1 shared Deepika GauriD· 1 shared Matthew L. WohleveriD· 1 shared S. P. AlleniD· 1 shared Sachini ThanthirigeiD· 1 shared Saeed A. BinsabaaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Banumathi SankaranORCID

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1 paper

Recent·Most cited

ALS mutations disrupt self-association between the Ubiquilin Sti1 hydrophobic groove and internal placeholder sequences

Joan Onwunma, Saeed A. Binsabaan, S. P. Allen, Sachini Thanthirige, Deepika Gaur, Banumathi Sankaran, Matthew L. Wohlever

This study presents the first crystal structure of the Ubiquilin Sti1 domain bound to a transmembrane domain, showing that ALS mutations disrupt their interaction and reveal internal placeholder sequences that regulate phase separation.

The EMBO Journal · Mar 20, 2026Peer-reviewedBiochemistry