A Mouse Model of SARS-CoV-2-Driven Acute Maladaptive Responses and Chronic Systemic Diseases
Devin Kenney, Giulia Unali, Anna E. Tseng, Joseph Léger, Mao Matsuo, Aoife Kateri O’Connell, Christina McConney, Samantha Good, Jack Norton, Fabiana Feitosa-Suntheimer, Mariano Carossino, Hans P. Gertje, Alexander D. Klose, Neal Paragas, Kevin P. Francis, , Florian Douam
The paper develops a mouse model that exhibits severe SARS-CoV-2 infection and post-acute systemic diseases, revealing molecular mechanisms of PASC.
bioRxiv · Aug 13, 2025 · PreprintMicrobiology