Author

Joerg Gsponer

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein design· 2 Research Focus:cell-cell communication· 1 Approach:diffusion model· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alireza OmidiiD· 1 shared Anna PrudovaiD· 1 shared Jennifer M. BuiiD· 1 shared Jiajun HeiD· 1 shared Leonard J. FosteriD· 1 shared Michael A. SkinnideriD· 1 shared Nichollas E. ScottiD· 1 shared Nikolay Stoynov· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alireza OmidiORCID

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2 papers

Recent·Most cited

De Novo Design of Protein Switches with Diffusion-Based Ensemble Sampling

Alireza Omidi, Jiajun He, Jennifer M. Bui, Joerg Gsponer, Saifuddin Syed

This paper introduces Diff-Switch, a method to generate switch-like protein backbone ensembles using diffusion models, improving success rates in multi-state inverse folding.

bioRxiv · Jul 21, 2026 · PreprintBioinformatics

An atlas of protein-protein interactions across mammalian tissues

Michael A. Skinnider, Nichollas E. Scott, Anna Prudova, Nikolay Stoynov, Richard Greg Stacey, Joerg Gsponer, Leonard J. Foster

This study maps protein-protein interactions across seven mouse tissues, revealing over 27,000 unique interactions and showing rewiring of interactions that is not predicted by gene expression.

bioRxiv · Jun 20, 2018 · PreprintSystems Biology