Author

Johann A Wehrstedt

University of Ottawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Amy E. HuttoniD· 1 shared Anthony P. GreeniD· 1 shared Behnoush SeifinoferestiD· 1 shared Jordan BerreuriD· 1 shared Linus O. JohannisseniD· 1 shared Michael C. ThompsoniD· 1 shared N. T. Hang PhamiD· 1 shared Roberto A. ChicaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Amy E. HuttonORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 14, 2026

Multistate Enzyme Design Enables Efficient and Stereoselective Multistep Catalysis

N. T. Hang Pham, Rui Guo, Rosalinda P Garcia Jimenez…·Roberto A. Chica

This paper introduces multistate enzyme design to optimize active sites across reaction coordinates, achieving higher catalytic efficiency and enantioselectivity than single-state designs.

DOI 10.64898/2026.09.11.750617

protein structureprotein sequence

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