Author

Amy E. Hutton

University of ManchesterORCID 0000-0003-1324-6627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein design· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Anthony P. GreeniD· 2 shared Alessia Andrews· 1 shared Behnoush SeifinoferestiD· 1 shared Clare F. MegarityiD· 1 shared Colin LevyiD· 1 shared David A. BakeriD· 1 shared Derren J. HeyesiD· 1 shared Elizabeth L. BelliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Anthony P. GreenORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 14, 2026

Multistate Enzyme Design Enables Efficient and Stereoselective Multistep Catalysis

N. T. Hang Pham, Rui Guo, Rosalinda P Garcia Jimenez…·Roberto A. Chica

This paper introduces multistate enzyme design to optimize active sites across reaction coordinates, achieving higher catalytic efficiency and enantioselectivity than single-state designs.

DOI 10.64898/2026.09.11.750617

protein structureprotein sequence

𝕏 PostBluesky

BiochemistryJournal of the American Chemical SocietyPeer-reviewedJul 9, 2026

A de novo CO2 Reductase Featuring a Cysteine-Ligated Cobalt Porphyrin Cofactor

Emily Radley, Alessia Andrews, Indrek Kalvet…·Anthony P. Green

This paper designs and tests hyper-thermostable CO2 reductases with cobalt porphyrin cofactors, achieving high activity and suppressing competing reactions.

3 citations

protein structuredeep learning

𝕏 PostBluesky