Reducing Reactive Lipids Improves Cardiac Metabolic and Diastolic Function in Pulmonary Hypertension Models
James D. West, Christy Moore, Santhi Gladson, Sheila Shay, Ethan Sevier, Elizabeth Kobeck, Ying Cai, Vineet Agrawal, John A. Rathmacher, Anna R. Hemnes
This study shows that reducing reactive lipids with 2-HOBA improves cardiac function and reduces pulmonary hypertension in mouse models.
bioRxiv · Oct 10, 2025Molecular Biology