Author

Elizabeth Kobeck

United States Department of Veterans Affairs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:mouse· 4 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Vineet AgrawaliD· 4 shared Anam FatimaiD· 2 shared Faris Abusharkh· 2 shared Fubiao ShiiD· 2 shared James D. WestiD· 2 shared Sheila CollinsiD· 2 shared Anna R. Hemnes· 1 shared Anna Ryan HemnesiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMolecular Biology

Vineet AgrawalORCID

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4 papers

Recent·Most cited

Nox4 Mediates Diastolic Function in a Genetic Model of Pitx2 Haploinsufficiency

Sumner L Gardner, Anam Fatima, Faris Abusharkh, Elizabeth Kobeck, Chitra Basu, Francis J. Miller, Vineet Agrawal

This study investigates the role of Nox4 in HFpEF-like remodeling in Pitx2 haploinsufficient mice, finding increased Nox4 expression and improved outcomes with GKT136901 treatment.

bioRxiv · Jul 1, 2026 · PreprintCell Biology

Wnt5a-mediated Adipo-Cardiac Interorgan Communication in HFpEF

Anam Fatima, Faris Abusharkh, Zoe Zanetta, Sumner Gardner, Fubiao Shi, Elizabeth Kobeck, Niki L. Fortune, Tuerdi Subati, Katherine N. Bachmann, Jonathan D. Brown, Deepak K. Gupta, David Armstrong, Jean W. Wassenaar, James D. West, Evan L. Brittain, , Vineet Agrawal

This study identifies a novel crosstalk mechanism between cardiomyocytes and adipocytes in obesity-associated HFpEF driven by natriuretic peptide-mediated inhibition of Wnt5a release from adipocytes.

bioRxiv · Oct 29, 2025 · PreprintMolecular Biology

Reducing Reactive Lipids Improves Cardiac Metabolic and Diastolic Function in Pulmonary Hypertension Models

James D. West, Christy Moore, Santhi Gladson, Sheila Shay, Ethan Sevier, Elizabeth Kobeck, Ying Cai, Vineet Agrawal, John A. Rathmacher, Anna R. Hemnes

This study shows that reducing reactive lipids with 2-HOBA improves cardiac function and reduces pulmonary hypertension in mouse models.

bioRxiv · Oct 10, 2025Molecular Biology

Salt-inducible kinase inhibition promotes weight loss and improves the diastolic function of obesity-related heart failure with preserved ejection fraction in mice

Fubiao Shi, Vineet Agrawal, Uugantsetseg Munkhjargal, Elizabeth Kobeck, Hari U. Patel, Wei Zhang, Sheila Collins

This study shows that inhibiting salt-inducible kinases (SIKs) reduces weight gain and improves diastolic heart function in obese mice with heart failure with preserved ejection fraction (HFpEF).

bioRxiv · Mar 2, 2025 · PreprintPhysiology