Author

John Drake

Virginia Commonwealth University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Research Focus:GWAS / association mapping· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Silviu‐Alin BacanuiD· 4 shared Vladimir I. VladimiroviD· 4 shared Ayman H. FanousiD· 2 shared Célia Barreto CarvalhoiD· 2 shared Eric VornholtiD· 2 shared Gowon O. McMichael· 2 shared Hamed KazemiiD· 2 shared Helena MedeirosiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Silviu‐Alin BacanuORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multiplex Portuguese Families as a Lens into rare mutations and the Shared Genetic Architecture of Schizophrenia, Mood Disorders, and Autism Spectrum Disorders

Carlos N. Pato, Michele T. Pato, Jennifer Mulle, Ronald P. Hart, Zhiping P. Pang, James A. Knowles, Tarjinder Singh, Priya Maddhesiya, Célia Barreto Carvalho, Alison K. Merikangas, Helena Medeiros, Christopher P. Morley, Tim B. Bigdeli, Hamed Kazemi, John Drake, , Ayman H. Fanous

This study analyzes 173 multiplex Portuguese families to identify rare genetic variants associated with schizophrenia, mood disorders, and autism, finding a CHD2 mutation linked to diverse mental illness phenotypes.

Genomic psychiatry : · Jun 16, 2026Peer-reviewedGenetic & Genomic Medicine

Gene-Set Based Rare Variant Association Analysis of Whole Genome Sequencing Data in the Portuguese Island Collection for Schizophrenia and Bipolar Disorder

Hamed Kazemi, John Drake, Tim Bigdeli, Silviu‐Alin Bacanu, Tan Hoang Nguyen, Kelly Suzanne Benke, Brion Maher, James Knowles, Steven A. McCarroll, Célia Barreto Carvalho, Helena Medeiros, Rute Ferreira, Michele T. Pato, Carlos Pato, Vladimir I. Vladimirov, Ayman H. Fanous

The paper performs rare variant association analysis using whole-genome sequencing data from the Portuguese Island Collection to identify shared genetic pathways in schizophrenia and bipolar disorder.

medRxiv · Jun 1, 2026 · PreprintGenetic & Genomic Medicine

Network Preservation Reveals Shared and Unique Biological Processes Associated with Chronic Alcohol Abuse in NAc and PFC.

Eric Vornholt, Mohammed Mamdani, John Drake, Gowon O. McMichael, Zachary N. Taylor, Silviu‐Alin Bacanu, Michael F. Miles, Vladimir I. Vladimirov

The paper identifies shared and unique biological processes in PFC and NAc associated with chronic alcohol abuse using network analysis and genetic regulatory mechanisms.

PLoS ONE · Dec 17, 2020Peer-reviewedGenomics

Assessing the role of long-noncoding RNA in nucleus accumbens in subjects with alcohol dependence

Gowon O. McMichael, John Drake, Eric Vornholt, Kellen G. Cresswell, Vernell S. Williamson, Chris Chatzinakos, Mohammed Mamdani, Siddharth P. Hariharan, Kenneth S. Kendler, Michael F. Miles, Gursharan Kalsi, Brien P. Riley, Mikhail G. Dozmorov, Silviu‐Alin Bacanu, Vladimir I. Vladimirov

The paper profiles lncRNA and protein coding gene expression in nucleus accumbens from alcohol-dependent and control subjects, identifying differentially expressed genes and their functional roles in alcohol dependence.

Alcoholism Clinical and Experimental Research · Oct 17, 2020Peer-reviewedNeuroscience