Michael F. Miles

The paper identifies myelin-associated gene expression and Ndrg1 as factors influencing initial alcohol sensitivity and consumption in prefrontal cortex.

This study identifies ethanol-regulated gene expression patterns in a mouse model of alcohol-induced peripheral neuropathy and highlights Jmjd1c as a potential candidate gene.

This study investigates the effects of chronic alcohol exposure on peripheral neuropathy in mice, identifying sex, intake duration, and acetaldehyde as key factors in neuroinflammation and hypersensitivity.

This study identifies genetic loci and subgroups in DO mice linked to anxiety-like behavior and ethanol consumption using behavioral assays and QTL analysis.

The paper shows that aligning RNA-seq data to strain-specific genomes increases the number of differentially expressed genes and exons detected when comparing C57BL/6J and DBA/2J mice.

This study shows that tideglusib, a GSK3β inhibitor, reduces ethanol consumption in mice without affecting water intake or anxiety-like behavior.

The paper investigates how GSK3B inhibition with tideglusib reverses ethanol-induced transcriptomic changes in mouse brains and links these findings to human genetic risk for alcohol dependence.

This study identifies QTL and candidate genes for ethanol-induced analgesia in BXD mouse strains using behavioral and bioinformatic analyses.

This study maps ethanol consumption traits in Diversity Outbred mice, identifying narrow QTLs and candidate genes, including Car8, with significant cis-eQTL linkage.

The paper identifies strain-specific alternative splicing differences in the Ninein gene between C57BL/6J and DBA/2J mice, linking these differences to ethanol anxiolytic effects.

The paper identifies genetic influences on ethanol consumption in Diversity Outbred mice by analyzing gene expression and eQTLs in the prefrontal cortex.

The paper analyzes rare functional variation in genes related to ethanol metabolism in severe alcohol dependence cases using a case-only design and WES data from the island of Ireland.

This study identifies oxidation-reduction processes as a mechanism linking Drosophila Clic to ethanol sensitivity through transcriptome analysis and functional experiments.

The paper identifies shared and unique biological processes in PFC and NAc associated with chronic alcohol abuse using network analysis and genetic regulatory mechanisms.

The paper profiles lncRNA and protein coding gene expression in nucleus accumbens from alcohol-dependent and control subjects, identifying differentially expressed genes and their functional roles in alcohol dependence.

The paper identifies brain regional gene expression networks affected by chronic ethanol exposure and consumption in mice, finding unique patterns in prefrontal cortex and nucleus accumbens.

This study shows that chronic repeated predatory stress reduces male mice's response to quinine adulteration of ethanol but not female mice's.

This study integrates mouse brain gene expression data with human genome-wide association data to identify novel gene networks associated with alcohol dependence.