Author

Priya Maddhesiya

Helmholtz Munich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Finja Berger· 2 shared Jovica NinkoviciD· 2 shared Magdalena GötziD· 2 shared Tatiana SimoniD· 2 shared Alessandro Zambusi· 1 shared Alison K. MerikangasiD· 1 shared Andrea Steiner-Mezzardi· 1 shared Anthodesmi Krontira· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Finja Berger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multiplex Portuguese Families as a Lens into rare mutations and the Shared Genetic Architecture of Schizophrenia, Mood Disorders, and Autism Spectrum Disorders

Carlos N. Pato, Michele T. Pato, Jennifer Mulle, Ronald P. Hart, Zhiping P. Pang, James A. Knowles, Tarjinder Singh, Priya Maddhesiya, Célia Barreto Carvalho, Alison K. Merikangas, Helena Medeiros, Christopher P. Morley, Tim B. Bigdeli, Hamed Kazemi, John Drake, , Ayman H. Fanous

This study analyzes 173 multiplex Portuguese families to identify rare genetic variants associated with schizophrenia, mood disorders, and autism, finding a CHD2 mutation linked to diverse mental illness phenotypes.

Genomic psychiatry : · Jun 16, 2026Peer-reviewedGenetic & Genomic Medicine

Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner

Priya Maddhesiya, Tjaša Lepko, Andrea Steiner-Mezzardi, Júlia Schneider, Veronika Schwarz, Juliane Merl‐Pham, Finja Berger, Stefanie M. Hauck, Lorenza Ronfani, Marco Emilio Bianchi, Tatiana Simon, Anthodesmi Krontira, Giacomo Masserdotti, Magdalena Götz, Jovica Ninkovic

The paper shows that Hmgb2 enhances astrocyte-to-neuron conversion by regulating chromatin accessibility of neuronal maturation genes in response to growth factors.

Genome biology · Apr 17, 2025Peer-reviewedNeuroscience

Stab Wound Injury Elicits Transit Amplifying Progenitor-like Phenotype in Parenchymal Astrocytes

Priya Maddhesiya, Finja Berger, Christina Koupourtidou, Alessandro Zambusi, Klara Tereza Novoselc, Judith Fischer-Sternjak, Tatiana Simon, Cora Olpe, Sebastian Jessberger, Magdalena Götz, Jovica Ninkovic

This study identifies injury-induced plastic astrocytes in mice that exhibit self-renewal and neurosphere-forming capabilities, resembling transit-amplifying progenitors in transcriptional profile.

bioRxiv · Sep 10, 2024 · PreprintNeuroscience