Author

John Jack

University of Western Macedonia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1

Frequent Co-Authors

Alexander Petrov· 1 shared Alexandra Kueider‐PaisleyiD· 1 shared Alison A. Motsinger‐ReifiD· 1 shared Amit Singh· 1 shared Andrew J. SaykiniD· 1 shared Ayesha Ali· 1 shared Colette BlachiD· 1 shared Cornelia M. van DuijniD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBioinformatics

Alexander Petrov

Author profile →

3 papers

Recent·Most cited

Proximity-Aware Graph Attention Networks for Spatially Resolved Cell-Cell Inference

Lucas Dubois, Alexander Petrov, John Jack

This paper introduces a proximity-aware graph attention network to infer cell-cell communication from spatial transcriptomics data, achieving improved performance over existing methods.

bioRxiv · Apr 23, 2026 · PreprintBioinformatics

Continual Learning for Emerging Epitope Landscapes in TCR peptide Binding Prediction

Amit Singh, Ayesha Ali, Deepak Yadav, John Jack

This paper introduces ContinualTCR, a continual learning framework for TCR peptide binding prediction that reduces catastrophic forgetting when adapting to new epitopes.

bioRxiv · Apr 23, 2026 · PreprintBioinformatics

Altered Bile Acid Profile Associates with Cognitive Impairment in Alzheimer’s Disease – An Emerging Role for Gut Microbiome

Siamak MahmoudianDehkordi, Matthias Arnold, Kwangsik T. Nho, Shahzad Ahmad, Wei Ping Jia, Guoxiang Xie, Gregory Louie, Alexandra Kueider‐Paisley, Martin Arthur Moseley, J. Will Thompson, Lisa St John Williams, Jessica D. Tenenbaum, Colette Blach, Rebecca Baillie, Xianlin Han, , Rima F Kaddurah-Daouk

The paper identifies altered bile acid profiles in Alzheimer's disease, linking them to cognitive impairment and genetic variants through a large study.

Alzheimer s & Dementia · Oct 15, 2018Peer-reviewedNeuroscience