J. Will Thompson

This paper evaluates a metabolomics workflow using microchip CE-MS with indexed migration time and single-point external calibration, showing improved accuracy and consistency across biological matrices.

The paper develops a streamlined workflow for proteomic analysis of proteins and PTMs from dried blood, demonstrating feasibility and best practices for MS-based quantification.

The paper develops SPE-CZE-MS for quantifying phosphorylated peptides in single-cell equivalent phosphoproteomics, demonstrating improved sensitivity and compatibility with mass spectrometry.

This study evaluates the interlaboratory reproducibility of the MxP(R) Quant 500 metabolomics/lipidomics kit across human and rodent blood samples, showing high consistency and reliability.

The paper uses targeted metabolomics to analyze changes in acylcarnitines, amines, and lipids in response to citalopram/escitalopram treatment in MDD patients, identifying metabolic correlates of treatment response.

The paper investigates sex and APOE ε4 genotype effects on metabolic alterations in Alzheimer’s disease using stratified analysis of serum metabolites.

The paper identifies altered bile acid profiles in Alzheimer's disease, linking them to cognitive impairment and genetic variants through a large study.