Author

John Jansen

Radboud University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Adrian King· 1 shared Antonio F. PardiñasiD· 1 shared Djenifer B. KappeliD· 1 shared Eilidh FenneriD· 1 shared Elliott ReesiD· 1 shared James WaltersiD· 1 shared Marinka Helthuis· 1 shared Michael C. O’DonovaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adrian King

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1 paper

Recent·Most cited

Rare Variants in Pharmacogenes Influence Clozapine Metabolism in Individuals with Schizophrenia

Djenifer B. Kappel, Elliott Rees, Eilidh Fenner, Adrian King, John Jansen, Marinka Helthuis, Michael John Owen, Michael C. O’Donovan, James Walters, Antonio F. Pardiñas

This study identifies rare genetic variants in pharmacogenes that influence clozapine metabolism in schizophrenia patients, with CYP1A2 variants showing the strongest effect.

European Neuropsychopharmacology · Feb 3, 2024Peer-reviewedGenetic & Genomic Medicine