Drug Response Prediction Provides a Biologically Relevant Benchmark for Perturbation Response Models
Niek Brouwer, Martin Damyanov, Jonas Argelo, Daniël J. Vis, Marcel J. T. Reinders, Lodewyk F.A. Wessels
The paper shows that drug response predictors trained on perturbation response model-generated profiles outperform those trained on baseline or pre-treatment profiles.
bioRxiv · Dec 11, 2025 · PreprintBioinformatics