Author

Niek Brouwer

Delft University of TechnologyORCID 0009-0005-8690-8371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Daniël J. VisiD· 1 shared Jonas Argelo· 1 shared Lodewyk F.A. WesselsiD· 1 shared Marcel J. T. ReindersiD· 1 shared Martin Damyanov· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBioinformatics

Daniël J. VisORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintDec 11, 2025

Drug Response Prediction Provides a Biologically Relevant Benchmark for Perturbation Response Models

Niek Brouwer, Martin Damyanov, Jonas Argelo…·Lodewyk F.A. Wessels

The paper shows that drug response predictors trained on perturbation response model-generated profiles outperform those trained on baseline or pre-treatment profiles.

DOI 10.64898/2025.12.09.693213

bulk RNA-seqmachine learning (classical)

𝕏 PostBluesky