New Drosophila models to uncover the intrinsic and extrinsic factors mediating the toxicity of the human prion protein
Ryan R. Myers, Jonatan Sanchez-Garcia, Daniel C. Levings, Richard G. Melvin, Pedro Fernández-Fúnez
The paper introduces a Drosophila model expressing human PrP to study intrinsic and extrinsic factors mediating its toxicity, identifying key cellular mechanisms and protective mutations.
Disease Models & Mechanisms · Feb 10, 2022Peer-reviewedNeuroscience