Author

Jonathan Assaad

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron N. HataiD· 1 shared Adam AckeriD· 1 shared Aleigha R. LawlessiD· 1 shared Alexander Healy· 1 shared Aliyu Sidi Omar Alghali· 1 shared Ana Carolina Martins DominguesiD· 1 shared Ann-Sophie Koglin· 1 shared Antonio Villanueva· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Aaron N. HataORCID

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1 paper

Recent·Most cited

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

Mariko Takahashi, Harrison Byron Chong, Siwen Zhang, Tzu-yi Yang, Matthew J. Lazarov, Stefan Andrew Harry, Michelle Maynard, Brendan J. Hilbert, Ryan D. White, Heather E. Murrey, Chih‐Chiang Tsou, Kira Vordermark, Jonathan Assaad, Magdy Gohar, Benedikt R. Dürr, , Liron Bar‐Peled

DrugMap quantitatively analyzes cysteine ligandability across 416 cancer cell lines, revealing redox state, conformational changes, and mutations as drivers of variability, and identifies covalent inhibitors targeting NFκB1 and SOX10.

Cell · Apr 22, 2024Peer-reviewedSystems Biology