The Role of Toll-like receptor 4 in respiratory syncytial virus replication, interferon lambda 1 induction, and chemokine responses.
Lindsay Broadbent, Jonathon D. Coey, Michael D. Shields, Ultan F. Power
This study investigates the role of TLR4 in RSV infection, IFN-λ1 induction, and chemokine responses using a human bronchial epithelial cell model, finding that TLR4 signaling through NF-κB and p38 MAPK mediates these effects.
bioRxiv · Aug 30, 2018 · PreprintMicrobiology