AI-Informed neoantigen prioritization enables a multi-epitope mRNA/LNP vaccine with antigen-specific immunogenicity and antitumor activity
Ayushi Verma, Sang Hoon Kim, Ban Seok Lee, Jong Hoo Lee, H J Kim, Hesung Now, Yoonjoo Choi, Dong‐Sup Lee, Woong‐Yang Park, Park Young Ae
This paper develops a multi-epitope mRNA/LNP vaccine using AI-prioritized neoantigens, showing enhanced immunogenicity and antitumor activity in preclinical models.
bioRxiv · Jul 10, 2026 · PreprintImmunology