Microgroove substrates unveil topography-driven, dynamic 3D nuclear deformations
Claire Leclech, Bettina Roellinger, Joni Frederick, Kamel Mamchaoui, Catherine Coirault, Abdul I. Barakat
This study uses microgroove substrates to show that adherent cells exhibit dynamic 3D nuclear deformations driven by adhesion, with implications for diagnosing nuclear mechanical disorders.
bioRxiv · Feb 2, 2024 · PreprintCell Biology