Catherine Coirault

This study uses a variational autoencoder to cluster nuclei on microgroove substrates, distinguishing between wildtype and laminopathy myoblasts based on nuclear deformation.

This study uses microgroove substrates to show that adherent cells exhibit dynamic 3D nuclear deformations driven by adhesion, with implications for diagnosing nuclear mechanical disorders.

This study shows that clathrin plaques and dynamin 2 anchor desmin intermediate filaments and regulate YAP signaling in skeletal muscle in response to mechanical cues.