Transgenic Targeting of Fcrls Creates a Highly Efficient Constitutively Active Microglia Cre Line with Differentiated Specificity
Tobias Kaiser, Jordan Dattero, Liang Li, Mandy Chen, Minqing Jiang, Andrew Harrahill, Oleg Butovsky, Guoping Feng
This paper introduces a constitutively active microglia-specific Cre line, Fcrls-2A-Cre, with high recombination efficiency and specificity, suitable for studies where tamoxifen is not feasible.
eNeuro · Jun 26, 2024Peer-reviewedNeuroscience