Master regulators governing protein abundance across ten human cancer types
Zishan Wang, Megan L. Wojciechowicz, Jordan Rosen, Abdülkadir Elmas, Won‐Min Song, Yansheng Liu, Kuan‐lin Huang
The paper identifies Master Protein abundance Regulators (MaPRs) across ten cancer types using a computational pipeline, finding they mediate up to 79% of post-transcriptional regulatory networks and predict tumor proteomic subtypes more accurately.
bioRxiv · Nov 11, 2024 · PreprintSystems Biology