Systems BiologybioRxivPreprint
Master regulators governing protein abundance across ten human cancer types
Zishan Wang, Megan L. Wojciechowicz, Jordan Rosen…·Kuan‐lin Huang
The paper identifies Master Protein abundance Regulators (MaPRs) across ten cancer types using a computational pipeline, finding they mediate up to 79% of post-transcriptional regulatory networks and predict tumor proteomic subtypes more accurately.
DOI 10.1101/2024.11.11.619147