Won‐Min Song

This study identifies ZNF180 as a driver of immunotherapy resistance in melanoma by promoting tumor plasticity and immune suppression through mechanisms involving MHC-I loss, CD155 expression, and CD4 T-cell exclusion.

This study identifies CLEC4E as a key driver of pro-inflammatory mDC responses in influenza using single-cell network analysis and validates its therapeutic potential in a murine model.

The paper uses single-nucleus RNA sequencing to analyze PSP brains and identifies dysregulation of the integrated stress response in vulnerable cell types.

The paper identifies Master Protein abundance Regulators (MaPRs) across ten cancer types using a computational pipeline, finding they mediate up to 79% of post-transcriptional regulatory networks and predict tumor proteomic subtypes more accurately.

The paper analyzes single-cell transcriptomic data from PSP brains to identify hybrid glial cell populations and their role in disease progression.

This study identifies molecular networks and key regulators in Alzheimer’s Disease using integrative genomics and experimental validation.