N-Methyl-D-Aspartate receptors control in vivo striatal calcium and the updating of action policy
Alex A. Legaria, Mason R. Barrett, Jordyn Czarny, Alexxai V. Kravitz
This study shows that NMDARs in the dorsomedial striatum are essential for learning from rewarded actions and that blocking them disrupts striatal calcium dynamics involved in updating action policies.
bioRxiv · Jul 10, 2026 · PreprintNeuroscience