Stem-Cell-Derived Islets as a Model of Human Islet Inflammation: A Comparative Analysis of Pro-inflammatory Cytokine Responses
Cecilie Amalie Brøgger Svane, Adam Bøgh Marstrand-Jørgensen, Anne Jørgensen, Rebekka H. Gerwig, Josefine Gudmann, Tina Fløyel, Tarunveer S. Ahluwalia, Flemming Pociot, Joachim Størling
This study compares the response of stem-cell-derived islets to pro-inflammatory cytokines with primary human islets and EndoC-{beta}H5 cells, showing similar functional and transcriptomic changes.
bioRxiv · May 3, 2026 · PreprintMolecular Biology