Author

Joachim Størling

University of CopenhagenORCID 0000-0002-7529-4264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne JørgenseniD· 2 shared Cecilie Amalie Brøgger SvaneiD· 2 shared Filip Krag KnopiD· 2 shared Kristine HenrikseniD· 2 shared Rebekka H. GerwigiD· 2 shared Adam Bøgh Marstrand-JørgenseniD· 1 shared Alexandra C. TitleiD· 1 shared Bolette HartmanniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Anne JørgensenORCID

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Author profile →

3 papers

Recent·Most cited

Stem-Cell-Derived Islets as a Model of Human Islet Inflammation: A Comparative Analysis of Pro-inflammatory Cytokine Responses

Cecilie Amalie Brøgger Svane, Adam Bøgh Marstrand-Jørgensen, Anne Jørgensen, Rebekka H. Gerwig, Josefine Gudmann, Tina Fløyel, Tarunveer S. Ahluwalia, Flemming Pociot, Joachim Størling

This study compares the response of stem-cell-derived islets to pro-inflammatory cytokines with primary human islets and EndoC-{beta}H5 cells, showing similar functional and transcriptomic changes.

bioRxiv · May 3, 2026 · PreprintMolecular Biology

Proinflammatory cytokine-induced alpha-cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism

Kristine Henriksen, Chantal Rufer, Alexandra C. Title, Sayro Jawurek, Bolette Hartmann, Jens Juul Holst, Filip Krag Knop, Burçak Yesildag, Joachim Størling

This paper shows that long-term cytokine exposure impairs alpha-cell glucagon secretion in human islet microtissues, which is partially restored by dual incretin receptor agonists.

Diabetologia · May 15, 2025Peer-reviewedCell Biology

Exploring the functional, protective, and transcriptomic effects of GIP on cytokine-exposed human pancreatic islets and EndoC-βH5 cells

Kristine Henriksen, Anne Jørgensen, Simranjeet Kaur, Rebekka H. Gerwig, Cecilie Amalie Brøgger Svane, Filip Krag Knop, Joachim Størling

This study investigates the functional, protective, and transcriptomic effects of GIP on cytokine-exposed human pancreatic islets and EndoC-βH5 cells, finding CaMK2-dependent insulinotropic effects but limited cytoprotection and transcriptomic modulation.

Molecular and Cellular Endocrinology · Mar 21, 2025Peer-reviewedCell Biology