Knockdown of Atg1 or Atg18 in adult adipocytes impairs lipophagy and reduces lifespan of fruit flies (Drosophila melanogaster)
Mariah Bierlein, Joseph Charles, Trevor Polisuk-Balfour, Heidi S. Bretscher, Micaela Rice, Jacklyn Zvonar, Drake Pohl, Lindsey Winslow, Brennah Wasie, Sara Deurloo, Jordan Van Wert, Britney Williams, Gabrielle Ankney, Zachary Harmon, Erica Dann, , Changqi C. Zhu
This study shows that knocking down Atg1 or Atg18 in adult fly adipocytes impairs lipophagy and reduces lifespan, but not in muscle or glia.
bioRxiv · Mar 22, 2023 · PreprintGenetics