Rare mutations implicate CGE interneurons as a vulnerable axis of cognitive deficits across psychiatric disorders
Stephanie A. Herrlinger, Jiayao Wang, Bovey Y. Rao, Erica Rodriguez, Jonathan Chang, Joseph Gogos, Attila Losonczy, Dennis Vitkup
The paper identifies CGE-derived GABAergic interneurons as a key target of rare mutations linked to cognitive deficits in ASD and SCZ using human and mouse models.
bioRxiv · Mar 28, 2025 · PreprintNeuroscience