Cell-type specific open chromatin profiling in human postmortem brain infers functional roles for non-coding schizophrenia loci
John F Fullard, Claudia Giambartolomei, Mads E Hauberg, Ke Hu, Christopher Bare, Joel T Dudley, Manuel Mattheisen, Joseph K Pickrell, Vahram Haroutunian, Panos Roussos
The paper uses ATAC-seq to profile open chromatin in human brain cells, identifying cell-type-specific regulatory elements and linking them to schizophrenia risk variants.
Human Molecular Genetics · Mar 14, 2017Peer-reviewedGenomics