Synergy with TGFβ ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation
Joseph Massey, Yida Liu, Omar E. Alvarenga, Teresa Saez, Matthew W. Schmerer, Aryeh Warmflash
The paper investigates how TGFβ ligands alter WNT/{beta}-catenin signaling dynamics during human pluripotent cell differentiation, showing a shift from transient to sustained responses.
Proceedings of the National Academy of Sciences · Feb 28, 2019Peer-reviewedDevelopmental Biology