Microvascular preservation and cardiomyocyte hyperplasia underlie adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension
Michael A. Smith, Eleana Stephanie Guardado, Jason B. Boehme, Sanjeev A. Datar, Emin Maltepe, Naveen Swami, Gary W. Raff, Aaron Bodansky, Prakash Chelladurai, Joseph Moreno, Annelise Renee Prince, Nevan Powers, Guo N. Huang, Vinicio de Jesús Pérez, Jeffrey R. Fineman
This study investigates adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension, finding preserved microvascular density and increased cardiomyocyte hyperplasia support RV function.
American Journal of Physiology-Heart and Circulatory Physiology · Sep 9, 2025Peer-reviewedPhysiology