Notch1 is required to maintain supporting cell identity and vestibular function during maturation of the mammalian balance organs
Alison M. Heffer, Choongheon Lee, Joseph P. Mayernik, Joseph C. Holt, Amy E. Kiernan
This study shows that Notch1 is critical for maintaining supporting cell identity in the vestibular organs, and its deletion leads to supporting cell conversion to hair cells and vestibular dysfunction.
Journal of Neuroscience · Jan 8, 2025Peer-reviewedDevelopmental Biology